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Review
Efficacy and side effects of Sputnik V, Sinopharm and AstraZeneca vaccines to stop COVID-19; a review and discussion
Nasrin Ghiasi
1 
, Rohollah Valizadeh
2 , Mohammad Arabsorkhi
3 , Tahere Sadat Hoseyni
4, Korosh Esfandiari
4, Tella Sadighpour
5* , Hamid Reza Jahantigh
6,71 Department of Midwifery, Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran
2 Student Research Committee, Department of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran
3 Medical Education Department, Medical Education Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
4 Ali-Asghar Children Hospital, Department of Radiology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
5 Herbert Wertheim College of Medicine, Florida international university, Florida, USA and American University of Antigua College of Medicine, Antigua and Barbuda
6 Interdisciplinary Department of Medicine - Section of Occupational Medicine, University of Bari, Bari, Italy
7 Animal Health and Zoonosis PhD Course, Department of Veterinary Medicine, University of Bari, Bari, Italy
*Corresponding Author: *Correspondence to Tella Sadighpour, Email: Tella.90s@gmail.com, tsadi003@fiu.edu, , Email:
tellas@auamed.net
Abstract
We believe that vaccination is just a way to eliminate or strongly stop the COVID-19. In this regard, there are several vaccines with different efficacy and side effects. It is urgently required to have some efficient vaccines for the prevention and control of SARS-CoV-2. In this review, international databases were considered for searching relevant articles from 1 January 2020 to 1 May 2021. Keywords were COVID-19, novel coronavirus, 2019- nCoV, coronavirus disease 2019, vaccine, Sputnik V, Gamaleya, Gam-COVID-Vac, Sinopharm, BBIBP-CorV, AstraZeneca, Vaxzevria, Oxford, ChAdOx1 nCoV-19 and AZD1222. Three Sputnik V, Sinopharm and AstraZeneca vaccines are useful to gain herd immunity. Enough intervals (at least three weeks/21 days) must be considered for sufficient neutralizing antibody titers. What is important is that the vaccination should be accelerated with each of the aforementioned three vaccines to achieve herd immunity in a shorter period of time because all three vaccines provide 100% prevention of severe COVID-19.
Citation: Ghiasi N, Valizadeh R, Arabsorkhi M, Hoseyni TS, Esfandiari K, Sadighpour T, Jahantigh HR. Efficacy and side effects of Sputnik V, Sinopharm and AstraZeneca vaccines to stop COVID-19; a review and discussion. Immunopathol Persa. 2021;7(2):e31. DOI:10.34172/ ipp.2021.31.